Since 1844 our mission has been to help Christians live out their desire to serve God with their whole lives and their whole selves. God asks us all to pray for ourselves and for others. To make ourselves a living sacrifice and to pray without ceasing for all the needs of the Church and for the whole world. Since the nineteenth century popes have asked the Apostleship of Prayer to pray for specific intentions. We receive two prayer intentions each month from the Holy Father, pledging ourselves to pray for them every day.

In 2006, the board of the Apostleship of Prayer approved this statement of our mission:

The mission of the Apostleship of Prayer is to encourage Christians to make a daily offering of themselves to the Lord for the coming of God's Kingdom and for the Holy Father's monthly intentions. This habit of prayer encourages a Eucharistic spirituality of solidarity with the Body of Christ and loving service to others. Nourishing this spiritual program is the love of the Sacred Heart of Jesus.